Step 1: Prepare Smear (e.g. blood or sputum)

Step 2: Fix in methanol

Step 3: Add Probe in Proprietary Hybridization Buffer

Step 4: Hybridize for 30 minutes

Step 5: Wash x3 in wash buffer at room temperature

Step 6: Add Mounting Medium

Step 7: View Under the Fluorescent Microscope with Appropriate filter at 1000X